Johns Hopkins Psychiatry Guide
Schizophrenia
DEFINITION
- A disorder characterized by psychotic symptoms, including hallucinations, delusions, or formal thought disorder, and accompanied by disorganized behaviors, negative symptoms, and/or a decline in premorbid functioning
- Negative symptoms: affective flattening, alogia (poverty of speech), anhedonia (inability to experience pleasure), avolition (lack of motivation), apathy (lack of interest), and/or social isolation[1]
- Positive symptoms: hallucinations, delusions, and/or formal thought disorder
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Last updated: September 1, 2025
Citation
Barisas, Derek, et al. "Schizophrenia." Johns Hopkins Psychiatry Guide, The Johns Hopkins University, 2025. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787043/all/Schizophrenia.
Barisas D, Solazzo S, Speed T, Sedlak T. Schizophrenia. Johns Hopkins Psychiatry Guide. The Johns Hopkins University; 2025. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787043/all/Schizophrenia. Accessed October 8, 2025.
Barisas, D., Solazzo, S., Speed, T., & Sedlak, T. (2025). Schizophrenia. In Johns Hopkins Psychiatry Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787043/all/Schizophrenia
Barisas D, Solazzo S, Speed T, Sedlak T. Schizophrenia [Internet]. In: Johns Hopkins Psychiatry Guide. The Johns Hopkins University; 2025. [cited 2025 October 08]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787043/all/Schizophrenia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Schizophrenia
ID - 787043
A1 - Barisas,Derek,M.D., Ph.D.
AU - Solazzo,Stephanie,M.D.
AU - Speed,Traci,M.D., Ph.D.
AU - Sedlak,Thomas,M.D., Ph.D.
Y1 - 2025/09/01/
BT - Johns Hopkins Psychiatry Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787043/all/Schizophrenia
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
