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Janessa Smith, Pharm.D., BCPS, Paul A. Pham, Pharm.D.
Leucovorin is a topic covered in the Johns Hopkins HIV Guide.

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  • Prophylaxis for drug-induced bone marrow toxicity (e.g methotrexate, pyrimethamine, or trimethoprim)
  • Antidote to the toxic effects of folic acid antagonists such as methotrexate, pyrimethamine, and trimethoprim.
  • Megaloblastic anemias associated with sprue, nutritional deficiency, pregnancy, and infancy when oral folic acid therapy cannot be given.

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Last updated: October 4, 2017


Smith, Janessa, and Paul A Pham. "Leucovorin." Johns Hopkins HIV Guide, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545119/all/Leucovorin.
Smith J, Pham PA. Leucovorin. Johns Hopkins HIV Guide. 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545119/all/Leucovorin. Accessed August 21, 2019.
Smith, J., & Pham, P. A. (2017). Leucovorin. In Johns Hopkins HIV Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545119/all/Leucovorin
Smith J, Pham PA. Leucovorin [Internet]. In: Johns Hopkins HIV Guide. ; 2017. [cited 2019 August 21]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545119/all/Leucovorin.
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TY - ELEC T1 - Leucovorin ID - 545119 A1 - Smith,Janessa,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2017/10/04/ BT - Johns Hopkins HIV Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545119/all/Leucovorin DB - Johns Hopkins Guide DP - Unbound Medicine ER -