Johns Hopkins HIV Guide
Emtricitabine
INDICATIONS
FDA
FDA
- Treatment of HIV-1 infection in combination with other antiretroviral agents
- Pre-exposure prophylaxis (PrEP) as a component of FDA-approved FTC/TDF or FTC/TAF fixed-dose combinations.
- FTC/TDF: adults and adolescents weighing ≥35 kg with potential sexual or injection-drug exposure.
- FTC/TAF: adults and adolescents weighing ≥35 kg with potential sexual exposure, excluding those likely to acquire HIV through receptive vaginal sex.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Treatment of hepatitis B in HIV-HBV co-infected patients as part of a fully suppressive ART regimen containing TAF or TDF plus FTC
- FTC should not be used as the sole HBV-active drug because HBV resistance emerges readily.
- Post-exposure prophylaxis (PEP) in combination with other agents.
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Last updated: September 7, 2026
Citation
Soto, Caitlin, and Janessa Smith. "Emtricitabine." Johns Hopkins HIV Guide, The Johns Hopkins University, 2026. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545063/all/Emtricitabine.
Soto C, Smith J. Emtricitabine. Johns Hopkins HIV Guide. The Johns Hopkins University; 2026. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545063/all/Emtricitabine. Accessed September 15, 2026.
Soto, C., & Smith, J. (2026). Emtricitabine. In Johns Hopkins HIV Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545063/all/Emtricitabine
Soto C, Smith J. Emtricitabine [Internet]. In: Johns Hopkins HIV Guide. The Johns Hopkins University; 2026. [cited 2026 September 15]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545063/all/Emtricitabine.
* Article titles in AMA citation format should be in sentence-case
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PB - The Johns Hopkins University
DB - Johns Hopkins Guides
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