Johns Hopkins Diabetes Guide
Somatostatinoma
DEFINITION
- Rare neuroendocrine tumors (NETs) that arise primarily in the pancreas (from D cells) and duodenum.
- May or may not secrete excess somatostatin, called somatostatinoma syndrome.
- Somatostatin inhibits the secretion of endocrine hormones including insulin which contributes to development of diabetes as well as paracrine hormones including cholecystokinin, vasoactive intestinal peptide (VIP), gastric inhibitory polypeptide (GIP), and pancreatic polypeptide (PP).[17]
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Last updated: June 9, 2020
Citation
Hamrahian, Amir, and Reshmi Srinath. "Somatostatinoma." Johns Hopkins Diabetes Guide, 2020. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/all/Somatostatinoma.
Hamrahian A, Srinath R. Somatostatinoma. Johns Hopkins Diabetes Guide. 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/all/Somatostatinoma. Accessed June 1, 2023.
Hamrahian, A., & Srinath, R. (2020). Somatostatinoma. In Johns Hopkins Diabetes Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/all/Somatostatinoma
Hamrahian A, Srinath R. Somatostatinoma [Internet]. In: Johns Hopkins Diabetes Guide. ; 2020. [cited 2023 June 01]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/all/Somatostatinoma.
* Article titles in AMA citation format should be in sentence-case
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