Johns Hopkins Diabetes Guide
Somatostatinoma
Somatostatinoma is a topic covered in the Johns Hopkins Diabetes Guide.
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DEFINITION
- Rare neuroendocrine tumors (NETs) that arise primarily in the pancreas (from D cells) and duodenum.
- May or may not secrete excess somatostatin, called somatostatinoma syndrome.
- Somatostatin inhibits the secretion of endocrine hormones including insulin which contributes to development of diabetes as well as paracrine hormones including cholecystokinin, vasoactive intestinal peptide (VIP), gastric inhibitory polypeptide (GIP), and pancreatic polypeptide (PP).[17]
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DEFINITION
- Rare neuroendocrine tumors (NETs) that arise primarily in the pancreas (from D cells) and duodenum.
- May or may not secrete excess somatostatin, called somatostatinoma syndrome.
- Somatostatin inhibits the secretion of endocrine hormones including insulin which contributes to development of diabetes as well as paracrine hormones including cholecystokinin, vasoactive intestinal peptide (VIP), gastric inhibitory polypeptide (GIP), and pancreatic polypeptide (PP).[17]
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Last updated: June 9, 2020
Citation
Hamrahian, Amir, and Reshmi Srinath. "Somatostatinoma." Johns Hopkins Diabetes Guide, 2020. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/4/Somatostatinoma.
Hamrahian A, Srinath R. Somatostatinoma. Johns Hopkins Diabetes Guide. 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/4/Somatostatinoma. Accessed September 25, 2021.
Hamrahian, A., & Srinath, R. (2020). Somatostatinoma. In Johns Hopkins Diabetes Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/4/Somatostatinoma
Hamrahian A, Srinath R. Somatostatinoma [Internet]. In: Johns Hopkins Diabetes Guide. ; 2020. [cited 2021 September 25]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547136/4/Somatostatinoma.
* Article titles in AMA citation format should be in sentence-case
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