Johns Hopkins Diabetes Guide
Lipids
Lipids is a topic covered in the Johns Hopkins Diabetes Guide.
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DESCRIPTION
- Standard lipid profile includes total cholesterol, triglycerides (TG), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and non-HDL cholesterol.
- Apolipoproteins and lipoprotein lipase activity can also be measured but are not recommend as part of standard analysis.
- Chylomicrons carry fat absorbed from the intestine.
- High LDL-C ("bad cholesterol”) is a strong risk factor for cardiovascular disease.
- Low HDL-C ("good cholesterol) is also a strong risk factor for cardiovascular disease.
- ApoB and Non-HDL-C (which includes LDL-C + Very LDL-C) are superior to LDL-C in quantifying atherosclerotic burden in patients with diabetes and/or hypertriglyceridemia. [3]
- High TG are also associated with cardiovascular disease although less strongly than high LDL-C, low HDL-C and non-HDL-C.
- Severe hypertriglyceridemia can also lead to pancreatitis in some individuals.
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DESCRIPTION
- Standard lipid profile includes total cholesterol, triglycerides (TG), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and non-HDL cholesterol.
- Apolipoproteins and lipoprotein lipase activity can also be measured but are not recommend as part of standard analysis.
- Chylomicrons carry fat absorbed from the intestine.
- High LDL-C ("bad cholesterol”) is a strong risk factor for cardiovascular disease.
- Low HDL-C ("good cholesterol) is also a strong risk factor for cardiovascular disease.
- ApoB and Non-HDL-C (which includes LDL-C + Very LDL-C) are superior to LDL-C in quantifying atherosclerotic burden in patients with diabetes and/or hypertriglyceridemia. [3]
- High TG are also associated with cardiovascular disease although less strongly than high LDL-C, low HDL-C and non-HDL-C.
- Severe hypertriglyceridemia can also lead to pancreatitis in some individuals.
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Last updated: October 10, 2021
Citation
Verma, Neha, et al. "Lipids." Johns Hopkins Diabetes Guide, 2021. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547085/all/Lipids.
Verma N, Joseph JJ, Margolis S. Lipids. Johns Hopkins Diabetes Guide. 2021. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547085/all/Lipids. Accessed October 17, 2021.
Verma, N., Joseph, J. J., & Margolis, S. (2021). Lipids. In Johns Hopkins Diabetes Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547085/all/Lipids
Verma N, Joseph JJ, Margolis S. Lipids [Internet]. In: Johns Hopkins Diabetes Guide. ; 2021. [cited 2021 October 17]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547085/all/Lipids.
* Article titles in AMA citation format should be in sentence-case
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T1 - Lipids
ID - 547085
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AU - Margolis,Simeon,M.D.
Y1 - 2021/10/10/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547085/all/Lipids
DB - Johns Hopkins Guide
DP - Unbound Medicine
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