Lipids
Neha Verma, M.D., Joshua J. Joseph, M.D. , Simeon Margolis, M.D.
DESCRIPTION
DESCRIPTION
DESCRIPTION
- Standard lipid profile includes total cholesterol, triglycerides (TG), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and non-HDL cholesterol.
- Apolipoproteins and lipoprotein lipase activity can also be measured but are not recommend as part of standard analysis.
- Chylomicrons carry fat absorbed from the intestine.
- High LDL-C ("bad cholesterol”) is a strong risk factor for cardiovascular disease.
- Low HDL-C ("good cholesterol) is also a strong risk factor for cardiovascular disease.
- ApoB and Non-HDL-C (which includes LDL-C + Very LDL-C) are superior to LDL-C in quantifying atherosclerotic burden in patients with diabetes and/or hypertriglyceridemia. [3]
- High TG are also associated with cardiovascular disease although less strongly than high LDL-C, low HDL-C and non-HDL-C.
- Severe hypertriglyceridemia can also lead to pancreatitis in some individuals.
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