Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:
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- Type 2 diabetes mellitus (T2DM) over the age of 65 years is a major public health problem.
- Many biological changes likely contribute to increased insulin resistance with aging including: increased abdominal fat mass, decreased physical activity, mitochondrial dysfunction, hormonal changes, increased oxidative stress and inflammation, lower density of the glucose carrier GLUT4 in the muscle.
- Presence of comorbidities, cognitive dysfunction and functional disabilities affect the management of diabetes, especially in the elderly.