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Diabetic Ketoacidosis

Diabetic Ketoacidosis is a topic covered in the Johns Hopkins Diabetes Guide.

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  • A metabolic acidosis characterized by the triad of hyperglycemia (glucose >250 mg/dL), metabolic acidosis (arterial pH ≤ 7.3, serum bicarbonate ≤ 18 meq/L) and moderate ketonuria or ketonemia
  • Most, but not all, patients have type 1 diabetes
  • Patients with type 2 diabetes also susceptible during acute illness (especially of African American or Hispanic descent) referred to as "ketosis-prone type 2 diabetes," likely due to greater relative insulinopenia[10].

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Last updated: November 5, 2015


Gonciulea, Anda, and Rita Rastogi Kalyani. "Diabetic Ketoacidosis." Johns Hopkins Diabetes Guide, 2015. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547037/all/Diabetic_Ketoacidosis.
Gonciulea A, Rastogi Kalyani R. Diabetic Ketoacidosis. Johns Hopkins Diabetes Guide. 2015. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547037/all/Diabetic_Ketoacidosis. Accessed May 19, 2019.
Gonciulea, A., & Rastogi Kalyani, R. (2015). Diabetic Ketoacidosis. In Johns Hopkins Diabetes Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547037/all/Diabetic_Ketoacidosis
Gonciulea A, Rastogi Kalyani R. Diabetic Ketoacidosis [Internet]. In: Johns Hopkins Diabetes Guide. ; 2015. [cited 2019 May 19]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547037/all/Diabetic_Ketoacidosis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Diabetic Ketoacidosis ID - 547037 A1 - Gonciulea,Anda,M.D. AU - Rastogi Kalyani,Rita,M.D., M.H.S. Y1 - 2015/11/05/ BT - Johns Hopkins Diabetes Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547037/all/Diabetic_Ketoacidosis DB - Johns Hopkins Guide DP - Unbound Medicine ER -