Johns Hopkins Diabetes Guide
Amyotrophy
DEFINITION
- An underdiagnosed condition referred to by different names including "diabetic proximal neuropathy," "diabetic lumbosacral radiculoplexopathy," and "Bruns-Garland syndrome".
- Classically, a monophasic illness characterized by acute to subacute onset of severe pain followed by subacute, progressive, asymmetrical limb muscle weakness a few weeks after with variable degrees of recovery.
- Patients often have some level of concurrent DPN.
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Last updated: January 5, 2017
Citation
Khoshnoodi, Nima, and Michael Polydefkis. "Amyotrophy." Johns Hopkins Diabetes Guide, The Johns Hopkins University, 2017. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547007/all/Amyotrophy.
Khoshnoodi N, Polydefkis M. Amyotrophy. Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547007/all/Amyotrophy. Accessed October 31, 2025.
Khoshnoodi, N., & Polydefkis, M. (2017). Amyotrophy. In Johns Hopkins Diabetes Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547007/all/Amyotrophy
Khoshnoodi N, Polydefkis M. Amyotrophy [Internet]. In: Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2017. [cited 2025 October 31]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547007/all/Amyotrophy.
* Article titles in AMA citation format should be in sentence-case
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T1 - Amyotrophy
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A1 - Khoshnoodi,Nima,M.D.
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Y1 - 2017/01/05/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547007/all/Amyotrophy
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
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