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Cardiobacterium species

Cardiobacterium species is a topic covered in the Johns Hopkins ABX Guide.

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  • Gram-negative bacillus, aerobic, on staining may be highly pleomorphic.
    • Part of upper respiratory human flora and occasionally on oral mucosal surfaces, it can be recovered in 70% of normal people.
    • Catalase-negative, oxidase-positive, indole-positive.
    • Slow-growing in traditional media
    • Low-virulence organism
    • Member of HACEK group that may cause endocarditis
  • Major species: Cardiobacterium hominis is the most common human pathogen species, through remains a rare infection overall.
    • Other species:
      • C. valvarum 
    • MALDI-ToF has been helpful at improving proper microbiologic identification.
  • Traditionally, a penicillin-sensitive organism, though in recent years, beta-lactamase production described in some isolates.
    • Aminoglycosides and fluoroquinolones also usually active.

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Last updated: April 5, 2019


"Cardiobacterium Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540710/0/Cardiobacterium_species.
Cardiobacterium species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540710/0/Cardiobacterium_species. Accessed August 18, 2019.
Cardiobacterium species. (2019). In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540710/0/Cardiobacterium_species
Cardiobacterium Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 August 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540710/0/Cardiobacterium_species.
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