Cardiobacterium species

Cardiobacterium species is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

Gram-negative bacillus, aerobic, on staining may be highly pleomorphic.
- Part of upper respiratory human flora and occasionally on oral mucosal surfaces, it can be recovered in 70% of normal people.
- Catalase-negative, oxidase-positive, indole-positive.
- Slow-growing in traditional media
- Low-virulence organism
- Member of HACEK group that may cause endocarditis
  - Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens and Kingella species
Major species: Cardiobacterium hominis is the most common human pathogen species, through remains a rare infection overall.
- Other species:
  - C. valvarum
- MALDI-ToF has been helpful at improving proper microbiologic identification.
Traditionally, a penicillin-sensitive organism, though in recent years, beta-lactamase production described in some isolates.
- Aminoglycosides and fluoroquinolones also usually active.

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MICROBIOLOGY

Gram-negative bacillus, aerobic, on staining may be highly pleomorphic.
- Part of upper respiratory human flora and occasionally on oral mucosal surfaces, it can be recovered in 70% of normal people.
- Catalase-negative, oxidase-positive, indole-positive.
- Slow-growing in traditional media
- Low-virulence organism
- Member of HACEK group that may cause endocarditis
  - Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens and Kingella species
Major species: Cardiobacterium hominis is the most common human pathogen species, through remains a rare infection overall.
- Other species:
  - C. valvarum
- MALDI-ToF has been helpful at improving proper microbiologic identification.
Traditionally, a penicillin-sensitive organism, though in recent years, beta-lactamase production described in some isolates.
- Aminoglycosides and fluoroquinolones also usually active.

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