Johns Hopkins ABX Guide
Plazomicin
INDICATIONS
FDA
FDA
- Complicated UTI[8][11][2]
- Including pyelonephritis, in adults ≥18 years with limited or no alternative treatment options.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Uncomplicated UTI[2]
- The 2026 IDSA AMR guidance lists single-dose aminoglycosides among preferred options for uncomplicated cystitis caused by ESBL-E or CRE; this is a class recommendation rather than a plazomicin-specific recommendation.
- Plague (Y. pestis)
- An alternative treatment (based on nonhuman, primate pneumonic plague model).[5]
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Last updated: September 6, 2026
Citation
Tsai, Y. V, and Kathryn Dzintars. "Plazomicin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2026. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540700/all/Plazomicin.
Tsai YV, Dzintars K. Plazomicin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2026. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540700/all/Plazomicin. Accessed September 22, 2026.
Tsai, Y. V., & Dzintars, K. (2026). Plazomicin. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540700/all/Plazomicin
Tsai YV, Dzintars K. Plazomicin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2026. [cited 2026 September 22]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540700/all/Plazomicin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Plazomicin
ID - 540700
A1 - Tsai,Y.,Pharm.D.
AU - Dzintars,Kathryn,Pharm.D., BCPS
Y1 - 2026/09/06/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540700/all/Plazomicin
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
