Plazomicin

Y. Vivian Tsai, Pharm.D., Kathryn Dzintars, Pharm.D., BCPS

INDICATIONS

INDICATIONS

INDICATIONS

FDA

FDA

FDA

  • Complicated UTI[8][11][2]
    • Including pyelonephritis, in adults ≥18 years with limited or no alternative treatment options.

NON-FDA APPROVED USES

NON-FDA APPROVED USES

NON-FDA APPROVED USES

  • Uncomplicated UTI[2]
    • The 2026 IDSA AMR guidance lists single-dose aminoglycosides among preferred options for uncomplicated cystitis caused by ESBL-E or CRE; this is a class recommendation rather than a plazomicin-specific recommendation.
  • Plague (Y. pestis)
    • An alternative treatment (based on nonhuman, primate pneumonic plague model).[5]

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