Johns Hopkins ABX Guide
Lung Abscess
Lung Abscess is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
Some pathogens that may routinely cause lung abscesses/cavities. Lung abscesses often polymicrobial and involve oral flora.
- Bacteria:
- S. aureus including MRSA and MSSA
- Anaerobes: most common cause; putrid sputum is diagnostic of this class of pathogens
- Fusobacterium nucleatum,Bacteroides melaninogenicus and Peptostreptococcus are leading anaerobic pathogens.
- Aerobic and microaerophilic streptococci including S. anginosus complex and Gr. A streptococci.
- Gram-negative bacteria, especially in Taiwan, an unexplained strong association with Klebsiella pneumoniae
- Also, P. aeruginosa.
- Meloidosis (Burkholderia pseudomallei) is a concern, especially in SE Asia.
- Legionella
- Nocardia
- Actinomyces
- Group A streptococci
- H. influenzae (type b)
- Rhodococcus equi
- Mycobacteria: M. tuberculosis, MAI, M. kansasii, M. abscessus
- Also, almost any non-tubercular mycobacteria may produce an abscess/cavity.
- Fungi: Aspergillus, Cryptococcus, Coccidioides, Histoplasma, Blastomyces, Fusarium, Mucor, Rhizopus
- Parasitic: usually more cystic
- Hydatid cysts (Echinococcus)
- Paragonimiasis
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PATHOGENS
Some pathogens that may routinely cause lung abscesses/cavities. Lung abscesses often polymicrobial and involve oral flora.
- Bacteria:
- S. aureus including MRSA and MSSA
- Anaerobes: most common cause; putrid sputum is diagnostic of this class of pathogens
- Fusobacterium nucleatum,Bacteroides melaninogenicus and Peptostreptococcus are leading anaerobic pathogens.
- Aerobic and microaerophilic streptococci including S. anginosus complex and Gr. A streptococci.
- Gram-negative bacteria, especially in Taiwan, an unexplained strong association with Klebsiella pneumoniae
- Also, P. aeruginosa.
- Meloidosis (Burkholderia pseudomallei) is a concern, especially in SE Asia.
- Legionella
- Nocardia
- Actinomyces
- Group A streptococci
- H. influenzae (type b)
- Rhodococcus equi
- Mycobacteria: M. tuberculosis, MAI, M. kansasii, M. abscessus
- Also, almost any non-tubercular mycobacteria may produce an abscess/cavity.
- Fungi: Aspergillus, Cryptococcus, Coccidioides, Histoplasma, Blastomyces, Fusarium, Mucor, Rhizopus
- Parasitic: usually more cystic
- Hydatid cysts (Echinococcus)
- Paragonimiasis
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Last updated: June 5, 2019
Citation
Auwaerter, Paul G, and John G Bartlett. "Lung Abscess." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540324/all/Lung_Abscess.
Auwaerter PG, Bartlett JG. Lung Abscess. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540324/all/Lung_Abscess. Accessed April 7, 2020.
Auwaerter, P. G., & Bartlett, J. G. (2019). Lung Abscess. In Johns Hopkins ABX Guide. The Johns Hopkins University. Retrieved April 07, 2020, from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540324/all/Lung_Abscess
Auwaerter PG, Bartlett JG. Lung Abscess [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2020 April 07]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540324/all/Lung_Abscess.
* Article titles in AMA citation format should be in sentence-case
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T1 - Lung Abscess
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AU - Bartlett,John,M.D.
Y1 - 2019/06/05/
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UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540324/all/Lung_Abscess
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
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