Johns Hopkins ABX Guide
Gentamicin
INDICATIONS
FDA
FDA
- Serious infections caused by susceptible strains of organisms.
- With the exception of uncomplicated UTI, aminoglycosides are generally used in combination for serious infections.
- Bacterial septicemia, including neonatal sepsis
- Skin, bone and soft tissue infections (including burns)
- Meningitis (poor penetration)
- Urinary tract
- Respiratory tract (poor penetration)
- Gastrointestinal tract (including peritonitis)
- Inflammatory ocular conditions that are steroid-responsive (ophthalmic ointment and suspension)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Pneumonia, hospital-acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third-/fourth-generation cephalosporin)
- Intra-abdominal infection (in combination with an agent with Gram-positive and anaerobe coverage)
- Enterococcal endocarditis (in combination with ampicillin)
- Pelvic inflammatory disease (PID, in combination with clindamycin)
- Brucella species
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Last updated: February 14, 2026
Citation
, Caitlin Soto, PharmD, BCIDP, and Kathryn Dzintars. "Gentamicin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2026. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin.
C, Dzintars K. Gentamicin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2026. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin. Accessed February 26, 2026.
, C., & Dzintars, K. (2026). Gentamicin. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin
C, Dzintars K. Gentamicin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2026. [cited 2026 February 26]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin.
* Article titles in AMA citation format should be in sentence-case
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PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
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