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    Chloramphenicol

    Paul A. Pham, Pharm.D., John G. Bartlett, M.D.
    Chloramphenicol is a topic covered in the Johns Hopkins ABX Guide.

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    -- The first section of this topic is shown below --

    INDICATIONS

    FDA

    • Note: for use only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated.
    • Acute infections caused by Salmonella typhi
    • Serious infections caused by Salmonella species, H. influenzae, specially meningeal infections, Rickettsia, Lymphogranuloma-psittacosis Chlamydia group, various Gram-negative bacteria causing bacteremia and meningitis.
    • Part of a cystic fibrosis regimen when other agents are ineffective or contraindicated.
    • Ocular infections (ophthalmic drops and ointments)

    NON-FDA APPROVED USES

    • Lung abscess
    • Gas gangrene (in PCN allergic pts)
    • Brain abscess
    • Paratyphoid fever
    • Q fever (Coxiella burnetii)
    • Rocky mountain spotted fever and other endemic (murine or scrub) typhus infections caused by Rickettsia species
    • Ehrlichiosis
    • Meningitis in PCN-allergic patients.

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    Last updated: January 31, 2016

    Citation

    Pham, Paul A, and John G Bartlett. "Chloramphenicol." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540119/all/Chloramphenicol.
    Pham PA, Bartlett JG. Chloramphenicol. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540119/all/Chloramphenicol. Accessed March 23, 2019.
    Pham, P. A., & Bartlett, J. G. (2016). Chloramphenicol. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540119/all/Chloramphenicol
    Pham PA, Bartlett JG. Chloramphenicol [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 March 23]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540119/all/Chloramphenicol.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Chloramphenicol ID - 540119 A1 - Pham,Paul,Pharm.D. AU - Bartlett,John,M.D. Y1 - 2016/01/31/ BT - Johns Hopkins ABX Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540119/all/Chloramphenicol PB - The Johns Hopkins University DB - Johns Hopkins Guide DP - Unbound Medicine ER -