Johns Hopkins ABX Guide
Burkholderia mallei
Burkholderia mallei is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Facultative, aerobic, nonmotile, slender, intracellular. Gram-negative rod.[3]
- Agent of glanders, a disease of solipeds
- Thrives intracellularly by modulating host immune-signaling pathways.[5]
- If suspected, notify lab personnel
- B. mallei is highly infectious as an aerosol.
- Classified as a Tier 1 biological select agent, https://www.selectagents.gov, accessed (9/1/19).
- Sometimes erroneously identified as Pseudomonas sp. by standard microbiologic testing, and B. mallei is morphologically indistinguishable from B. pseudomallei.
- Hard to see on Gram stain. Grows slowly, best with glycerol.
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MICROBIOLOGY
- Facultative, aerobic, nonmotile, slender, intracellular. Gram-negative rod.[3]
- Agent of glanders, a disease of solipeds
- Thrives intracellularly by modulating host immune-signaling pathways.[5]
- If suspected, notify lab personnel
- B. mallei is highly infectious as an aerosol.
- Classified as a Tier 1 biological select agent, https://www.selectagents.gov, accessed (9/1/19).
- Sometimes erroneously identified as Pseudomonas sp. by standard microbiologic testing, and B. mallei is morphologically indistinguishable from B. pseudomallei.
- Hard to see on Gram stain. Grows slowly, best with glycerol.
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Last updated: October 1, 2019
Citation
Spacek, Lisa A, and John G Bartlett. "Burkholderia Mallei." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540070/all/Burkholderia_mallei.
Spacek LA, Bartlett JG. Burkholderia mallei. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540070/all/Burkholderia_mallei. Accessed January 29, 2020.
Spacek, L. A., & Bartlett, J. G. (2019). Burkholderia mallei. In Johns Hopkins ABX Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540070/all/Burkholderia_mallei
Spacek LA, Bartlett JG. Burkholderia Mallei [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2020 January 29]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540070/all/Burkholderia_mallei.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Burkholderia mallei
ID - 540070
A1 - Spacek,Lisa,M.D., Ph.D.
AU - Bartlett,John,M.D.
Y1 - 2019/10/01/
BT - Johns Hopkins ABX Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540070/all/Burkholderia_mallei
PB - The Johns Hopkins University
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -