Burkholderia mallei
Burkholderia mallei is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Facultative, aerobic, nonmotile, slender, intracellular. Gram-negative rod.[3]
- Agent of glanders, a disease of solipeds
- Thrives intracellularly by modulating host immune-signaling pathways.[5]
- If suspected, notify lab personnel
- B. mallei is highly infectious as an aerosol.
- Classified as a Tier 1 biological select agent, https://www.selectagents.gov, accessed (9/1/19).
- Sometimes erroneously identified as Pseudomonas sp. by standard microbiologic testing, and B. mallei is morphologically indistinguishable from B. pseudomallei.
- Hard to see on Gram stain. Grows slowly, best with glycerol.
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MICROBIOLOGY
- Facultative, aerobic, nonmotile, slender, intracellular. Gram-negative rod.[3]
- Agent of glanders, a disease of solipeds
- Thrives intracellularly by modulating host immune-signaling pathways.[5]
- If suspected, notify lab personnel
- B. mallei is highly infectious as an aerosol.
- Classified as a Tier 1 biological select agent, https://www.selectagents.gov, accessed (9/1/19).
- Sometimes erroneously identified as Pseudomonas sp. by standard microbiologic testing, and B. mallei is morphologically indistinguishable from B. pseudomallei.
- Hard to see on Gram stain. Grows slowly, best with glycerol.
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