- Community-acquired pneumonia of mild severity (20%-30% of S. pneumoniae strains resistant to azithromycin but clinical significance unknown)
- FDA-approved for adults and children (6 months and older)
- Pharyngitis (adults and children older than 2 years)
- Acute bacterial sinusitis(adults)
- Acute otitis media (pediatric, 6 months of age and older)
- Acute bacterial exacerbations of chronic obstructive pulmonary disease(adults)
- Treatment and prophylaxis of disseminated M. avium infection (treatment requires co-administration with ethambutol)
- Uncomplicated skin and skin structure infections(adults)
- Urethritis and cervicitis (caused by C. trachomatis)
- Please see the modules for the latest recommendations.
- Genital ulcer disease
- Please see the module for the latest recommendations.
NON-FDA APPROVED USES
It is not a comprehensive listing, but azithromycin is commonly employed in the following:
- Babesiosis (in combination with atovaquone)
- Toxoplasmosis (with pyrimethamine)
- Meningococcal meningitis prophylaxis
- Falciparum malaria (in combination with artesunate), uncomplicated disease
- Anti-inflammatory therapy in cystic fibrosis or bronchiectasis
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