Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:
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- Facultative anaerobic Gram negative rod.
- Non-lactose fermenter in the same family as Proteus.
- Environmentally ubiquitous, part of normal colonic flora.
- "Urea splitter," but stones seen less frequently than Proteus due to less effective urease enzyme.
- Morganella only has single member in its genus M. morganii, and two subspecies: M. morganii and M. sibonii, which differ only in trehalose fermentation.
- Antimicrobial susceptibility:
- Naturally resistant to penicillin, 1st-2nd generation cephalosporins, macrolides, sulfamethoxazole .
- Beta-lactamase is inducible, chromosomal AmpC type. May confer resistance to imipenem in some isolates.
- Tigecycline not reliably effective due to ArcAB efflux pump, although may show synergy in vitro with other antimicrobials [ref].
- Extended spectrum beta-lactamases, inducible beta-lactamases, carbapenemases including New Delhi metallo-β-lactamase 1 (NDM-1) and fluoroquinolone resistance reported.