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Nathalie Szilagyi, Margaret S. Chisolm, M.D.
Pathoplasticity is a topic covered in the Johns Hopkins Psychiatry Guide.

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  • Pathoplasticity is the “variability in a symptom’s specific form and content, shaped by events in a patient’s life.”[1]
  • Pathoplastic features are differentiated from pathognomonic features, which are specifically distinctive or characteristic of a disease or pathologic condition.
    • The clinician can make a diagnosis based on pathognomonic signs and symptoms, but pathoplastic features by definition can vary between individuals with the same diagnosis.

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Last updated: January 29, 2017


Szilagyi, Nathalie, and Margaret S Chisolm. "Pathoplasticity." Johns Hopkins Psychiatry Guide, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787167/all/Pathoplasticity.
Szilagyi N, Chisolm MS. Pathoplasticity. Johns Hopkins Psychiatry Guide. 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787167/all/Pathoplasticity. Accessed July 18, 2019.
Szilagyi, N., & Chisolm, M. S. (2017). Pathoplasticity. In Johns Hopkins Psychiatry Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787167/all/Pathoplasticity
Szilagyi N, Chisolm MS. Pathoplasticity [Internet]. In: Johns Hopkins Psychiatry Guide. ; 2017. [cited 2019 July 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787167/all/Pathoplasticity.
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TY - ELEC T1 - Pathoplasticity ID - 787167 A1 - Szilagyi,Nathalie, AU - Chisolm,Margaret,M.D. Y1 - 2017/01/29/ BT - Johns Hopkins Psychiatry Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787167/all/Pathoplasticity DB - Johns Hopkins Guide DP - Unbound Medicine ER -