Johns Hopkins Psychiatry Guide
Perinatal Mood Disorders
DEFINITION
- Major depression with perinatal onset (includes postpartum depression)
- "Perinatal depression" refers to a major depressive episode that occurs during pregnancy or within 4 weeks following delivery.
- "Postpartum depression" refers to an episode of major depression that begins within the first 4 weeks after delivery.
- Perinatal mood and anxiety disorders (PMADs) are the #1 complication of pregnancy and childbirth. In 2017, the estimated cost incurred by mothers and their babies of untreated PMADs from conception through the first 5 years of the birth cohort’s lives was $14 billion.[1]
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Last updated: August 31, 2025
Citation
Olson, Elizabeth, et al. "Perinatal Mood Disorders." Johns Hopkins Psychiatry Guide, The Johns Hopkins University, 2025. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787152/2.2/Perinatal_Mood_Disorders.
Olson E, Kimmel M, Payne J. Perinatal Mood Disorders. Johns Hopkins Psychiatry Guide. The Johns Hopkins University; 2025. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787152/2.2/Perinatal_Mood_Disorders. Accessed October 8, 2025.
Olson, E., Kimmel, M., & Payne, J. (2025). Perinatal Mood Disorders. In Johns Hopkins Psychiatry Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787152/2.2/Perinatal_Mood_Disorders
Olson E, Kimmel M, Payne J. Perinatal Mood Disorders [Internet]. In: Johns Hopkins Psychiatry Guide. The Johns Hopkins University; 2025. [cited 2025 October 08]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787152/2.2/Perinatal_Mood_Disorders.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Perinatal Mood Disorders
ID - 787152
A1 - Olson,Elizabeth,M.D.
AU - Kimmel,Mary,M.D.
AU - Payne,Jennifer,M.D.
Y1 - 2025/08/31/
BT - Johns Hopkins Psychiatry Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787152/2.2/Perinatal_Mood_Disorders
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
