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Dementia with Lewy Bodies

Tamela McClam, M.D., Gregory Pontone, M.D.
Dementia with Lewy Bodies is a topic covered in the Johns Hopkins Psychiatry Guide.

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DEFINITION

  • Dementia with Lewy bodies (DLB) is a primary neurodegenerative disorder affecting cognitive function and movement.
    • Early symptoms include prominent deficits in attention, as well as visuospatial and executive dysfunction.
    • Additional features include parkinsonism, hallucinations, cognitive fluctuations, and REM sleep behavior disorder.
  • One of the synucleinopathies
    • Lewy bodies: abnormal protein aggregates composed of α-synuclein
  • Cognitive impairment due to Lewy bodies is classified under the neurocognitive disorders (NCDs) section of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5)[1].

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Last updated: March 1, 2017

Citation

McClam, Tamela, and Gregory Pontone. "Dementia With Lewy Bodies." Johns Hopkins Psychiatry Guide, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787109/all/Dementia_with_Lewy_Bodies.
McClam T, Pontone G. Dementia with Lewy Bodies. Johns Hopkins Psychiatry Guide. 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787109/all/Dementia_with_Lewy_Bodies. Accessed March 21, 2019.
McClam, T., & Pontone, G. (2017). Dementia with Lewy Bodies. In Johns Hopkins Psychiatry Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787109/all/Dementia_with_Lewy_Bodies
McClam T, Pontone G. Dementia With Lewy Bodies [Internet]. In: Johns Hopkins Psychiatry Guide. ; 2017. [cited 2019 March 21]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787109/all/Dementia_with_Lewy_Bodies.
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TY - ELEC T1 - Dementia with Lewy Bodies ID - 787109 A1 - McClam,Tamela,M.D. AU - Pontone,Gregory,M.D. Y1 - 2017/03/01/ BT - Johns Hopkins Psychiatry Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787109/all/Dementia_with_Lewy_Bodies DB - Johns Hopkins Guide DP - Unbound Medicine ER -