Frontotemporal Dementia
Frontotemporal Dementia is a topic covered in the Johns Hopkins Psychiatry Guide.
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DEFINITION
- Frontotemporal dementia (FTD) is a clinically and histopathologically heterogeneous neurodegenerative disorder that presents as a focal disorder of conduct, temperament, judgment, and/or speech and language.
- Three canonical syndromes are recognized:
- Behavior variant FTD (bvFTD): the commonest; characterized by a focal decline in conduct, temperament, and judgment
- Primary progressive aphasia (PPA) variants: primary non-fluent aphasia features halting, telegraphic speech with agrammatism and phonological errors
- Semantic dementia: manifests progressive anomia, with focal loss of word and object knowledge, and fluent and vacuous speech with semantic errors
- In time, the illness includes a wider range of cognitive deficits.
- Frontotemporal lobar degeneration refers to the histopathological state that underlies the clinical syndromes.
- Cognitive impairment due to frontotemporal dementia is classified under the neurocognitive disorders (NCDs) section of the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5).[1]
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Last updated: March 1, 2017
Citation
McClam, Tamela, and Chiadi Onyike. "Frontotemporal Dementia." Johns Hopkins Psychiatry Guide, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787108/3.1/Frontotemporal_Dementia.
McClam T, Onyike C. Frontotemporal Dementia. Johns Hopkins Psychiatry Guide. 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787108/3.1/Frontotemporal_Dementia. Accessed August 23, 2019.
McClam, T., & Onyike, C. (2017). Frontotemporal Dementia. In Johns Hopkins Psychiatry Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787108/3.1/Frontotemporal_Dementia
McClam T, Onyike C. Frontotemporal Dementia [Internet]. In: Johns Hopkins Psychiatry Guide. ; 2017. [cited 2019 August 23]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787108/3.1/Frontotemporal_Dementia.
* Article titles in AMA citation format should be in sentence-case
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