Johns Hopkins Psychiatry Guide

Hallucinogen-Related Disorders

Albert Garcia-Romeu, Ph.D., Alexis S. Hammond, M.D., Ph.D., Denis Antoine, M.D.
Hallucinogen-Related Disorders is a topic covered in the Johns Hopkins Psychiatry Guide.

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DEFINITION

  • A group of substance-related disorders involving the ingestion of drugs classified broadly as hallucinogens
  • In the DSM, hallucinogens are subdivided into two main categories:
    • Phencyclidine: Used for phencyclidine (PCP) and related compounds including: ketamine, cyclohexamine, and dizocilpine
    • Other hallucinogen: Used for all other hallucinogens including phenylalkylamines (e.g., mescaline, DOM, and MDMA), indoleamines (e.g. psilocybin and DMT), ergolines (e.g., LSD and morning glory seeds), and phenethylamines (e.g., 25I-NBOMe)
  • Disorders caused by PCP and related compounds are include:
    • Phencyclidine use disorder: Pattern of phencyclidine (PCP) or related substance (e.g., ketamine) use causing significant concern or harm, and decrease in functioning
    • Phencyclidine intoxication: Behavioral effects occurring after ingestion of PCP or a related substance (e.g., ketamine)
    • Other phencyclidine-induced disorders:
      • PCP-induced psychotic disorder (see schizophrenia spectrum), PCP-induced depressive disorder, PCP-induced bipolar affective disorder, PCP-induced anxiety disorder, PCP-induced intoxication delirium
    • Unspecified phencyclidine-related disorder: A PCP-related disorder causing significant concern or harm, and decrease in functioning, not meeting full criteria for any particular PCP-related disorders
  • Disorders caused by other hallucinogens include:
    • Other hallucinogen use disorder: Pattern of "other hallucinogen" use causing significant concern or harm, and decrease in functioning
    • Other hallucinogen intoxication: Behavioral or psychological effects occurring after ingestion of a hallucinogen (other than PCP).
    • Other hallucinogen-induced disorders
      • Other hallucinogen-induced psychotic disorder (see schizophrenia spectrum), other hallucinogen-induced depressive disorder, other hallucinogen-induced bipolar affective disorder, other hallucinogen-induced anxiety disorder, other hallucinogen intoxication delirium
    • Unspecified hallucinogen-related disorder: A hallucinogen-related disorder causing significant concern or harm, and decrease in functioning, not meeting full criteria for any specific other hallucinogen-related disorders
  • Hallucinogen persisting perception disorder
    • Re-experiencing while sober the perceptual (often visual) disturbances experienced when an individual was intoxicated with a hallucinogen

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Last updated: May 2, 2017