- All forms of tuberculosis.
- Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx.
- Rifampin is used to reduce the development of drug-resistant bacteria and other antibacterial drugs--used only to treat or prevent infections proven or strongly suggested to be caused by bacteria.
NON-FDA APPROVED USES
- Anthrax infections
- Bartonella infections
- H. influenzae disease, chemoprophylaxis after close contact with a patient with invasive disease
- Legionella infections
- Meningitis caused by penicillin and ceftriaxone-resistantS. pneumoniae
- N. meningitidis, chemoprophylaxis after close contact with a patient with invasive disease
- Non-tuberculous mycobacterial infections (e.g., leprosy, MAC)
- Prosthetic joint infections following debridement and retention of the prosthesis or 1-stage exchange.
- Prosthetic valve endocarditis caused by staphylococci in combination with other agents (e.g., oxacillin/nafcillin, vancomycin) after blood cultures have cleared.
- Q-fever and rickettsial infections
- Used mainly in pregnant women
- NOTE: Rifampin is usually used in combination with other agents due to the quick emergence of resistance if used as monotherapy.
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