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    HMG CoA Reductase Inhibitors ("Statins")

    Janessa M. Smith, PharmD, BCPS, Paul A. Pham, Pharm.D.
    HMG CoA Reductase Inhibitors ("Statins") is a topic covered in the Johns Hopkins HIV Guide.

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    INDICATIONS

    FDA

    • Atherosclerosis: fluvastatin, lovastatin
    • Cardiovascular events (secondary prevention): pravastatin; coronary heart disease (primary prevention): pravastatin, simvastatin, fluvastatin, lovastatin
    • Stroke / TIA (prophylaxis): simvastatin, rosuvastatin, atorvastatin
    • Hypercholesterolemia, heterozygous familial: pravastatin (pediatrics), fluvastatin, atorvastatin, lovastatin, rosuvastatin; hypercholesterolemia, homozygous familial: simvastatin, atorvastatin, rosuvastatin
    • Hypercholesterolemia (primary): fluvastatin, rosuvastatin, lovastatin, atorvastatin; hypertriglyceridemia: atorvastatin, rosuvastatin

    NON-FDA APPROVED USES

    • Hyperlipidemia associated with ART

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    Last updated: September 3, 2016

    Citation

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    TY - ELEC T1 - HMG CoA Reductase Inhibitors ("Statins") ID - 545193 A1 - Pham,Paul,Pharm.D. AU - Smith,Janessa,PharmD, BCPS Y1 - 2016/09/03/ BT - Johns Hopkins HIV Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_ DB - Johns Hopkins Guide DP - Unbound Medicine ER -