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HMG CoA Reductase Inhibitors ("Statins")

Janessa M. Smith, PharmD, BCPS, Paul A. Pham, Pharm.D.
HMG CoA Reductase Inhibitors ("Statins") is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Atherosclerosis: fluvastatin, lovastatin
  • Cardiovascular events (secondary prevention): pravastatin; coronary heart disease (primary prevention): pravastatin, simvastatin, fluvastatin, lovastatin
  • Stroke / TIA (prophylaxis): simvastatin, rosuvastatin, atorvastatin
  • Hypercholesterolemia, heterozygous familial: pravastatin (pediatrics), fluvastatin, atorvastatin, lovastatin, rosuvastatin; hypercholesterolemia, homozygous familial: simvastatin, atorvastatin, rosuvastatin
  • Hypercholesterolemia (primary): fluvastatin, rosuvastatin, lovastatin, atorvastatin; hypertriglyceridemia: atorvastatin, rosuvastatin

NON-FDA APPROVED USES

  • Hyperlipidemia associated with ART

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Last updated: September 3, 2016

Citation

Smith, Janessa M, and Paul A Pham. "HMG CoA Reductase Inhibitors ("Statins")." Johns Hopkins HIV Guide, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_.
Smith JM, Pham PA. HMG CoA Reductase Inhibitors ("Statins"). Johns Hopkins HIV Guide. 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_. Accessed May 20, 2019.
Smith, J. M., & Pham, P. A. (2016). HMG CoA Reductase Inhibitors ("Statins"). In Johns Hopkins HIV Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_
Smith JM, Pham PA. HMG CoA Reductase Inhibitors ("Statins") [Internet]. In: Johns Hopkins HIV Guide. ; 2016. [cited 2019 May 20]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - HMG CoA Reductase Inhibitors ("Statins") ID - 545193 A1 - Smith,Janessa,PharmD, BCPS AU - Pham,Paul,Pharm.D. Y1 - 2016/09/03/ BT - Johns Hopkins HIV Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_ DB - Johns Hopkins Guide DP - Unbound Medicine ER -