HMG CoA Reductase Inhibitors ("Statins")

Janessa M. Smith, PharmD, BCPS, Paul A. Pham, Pharm.D.

HMG CoA Reductase Inhibitors ("Statins") is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

Atherosclerosis: fluvastatin, lovastatin
Cardiovascular events (secondary prevention): pravastatin; coronary heart disease (primary prevention): pravastatin, simvastatin, fluvastatin, lovastatin
Stroke / TIA (prophylaxis): simvastatin, rosuvastatin, atorvastatin
Hypercholesterolemia, heterozygous familial: pravastatin (pediatrics), fluvastatin, atorvastatin, lovastatin, rosuvastatin; hypercholesterolemia, homozygous familial: simvastatin, atorvastatin, rosuvastatin
Hypercholesterolemia (primary): fluvastatin, rosuvastatin, lovastatin, atorvastatin; hypertriglyceridemia: atorvastatin, rosuvastatin

NON-FDA APPROVED USES

Hyperlipidemia associated with ART

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Last updated: September 3, 2016

Citation

Smith, Janessa M, and Paul A Pham. "HMG CoA Reductase Inhibitors ("Statins")." Johns Hopkins HIV Guide, Johns Hopkins Guide, 21 September 2018, https://www.unboundmedicine.com/medline/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_. Accessed 21 September 2018.

Smith JM, Pham PA. (Published September 21, 2018). HMG CoA Reductase Inhibitors ("Statins"). Johns Hopkins HIV Guide, Johns Hopkins Guide. Retrieved from https://www.unboundmedicine.com/medline/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_

Smith, J. M., & Pham, P. A. HMG CoA Reductase Inhibitors ("Statins"). Johns Hopkins Guide. Johns Hopkins HIV Guide. https://www.unboundmedicine.com/medline/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_. Published 2018.

Smith JM, Pham PA. Johns Hopkins HIV Guide [Internet]. c2018. HMG CoA Reductase Inhibitors ("Statins"); Johns Hopkins Guide. [cited 2018 September 21]; Available from: https://www.unboundmedicine.com/medline/view/Johns_Hopkins_HIV_Guide/545193/all/HMG_CoA_Reductase_Inhibitors__"Statins"_

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