HMG CoA Reductase Inhibitors ("Statins")

Janessa M. Smith, PharmD, BCPS, Paul A. Pham, Pharm.D.
HMG CoA Reductase Inhibitors ("Statins") is a topic covered in the Johns Hopkins HIV Guide.

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  • Atherosclerosis: fluvastatin, lovastatin
  • Cardiovascular events (secondary prevention): pravastatin; coronary heart disease (primary prevention): pravastatin, simvastatin, fluvastatin, lovastatin
  • Stroke / TIA (prophylaxis): simvastatin, rosuvastatin, atorvastatin
  • Hypercholesterolemia, heterozygous familial: pravastatin (pediatrics), fluvastatin, atorvastatin, lovastatin, rosuvastatin; hypercholesterolemia, homozygous familial: simvastatin, atorvastatin, rosuvastatin
  • Hypercholesterolemia (primary): fluvastatin, rosuvastatin, lovastatin, atorvastatin; hypertriglyceridemia: atorvastatin, rosuvastatin


  • Hyperlipidemia associated with ART

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Last updated: September 3, 2016