Rifabutin is a topic covered in the Johns Hopkins HIV Guide.

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INDICATIONS

FDA

  • Prophylaxis of MAC in pts with AIDS

NON-FDA APPROVED USES

  • Treatment of disseminated MAC in pts with AIDS (in combination with macrolide plus EMB)
  • Treatment of TB in pts with AIDS who are taking PIs or NNRTIs
  • Treatment of latent TB in pts intolerant to INH. Rifabutin x 4 mos can be considered.

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Last updated: November 9, 2011