Pseudomonas aeruginosa
Pseudomonas aeruginosa is a topic covered in the Johns Hopkins HIV Guide.
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MICROBIOLOGY
- Aerobic, motile, oxidase-positive, non-fermenting, Gram-negative bacillus.
- Ubiquitous, isolated from soil, water, plants, and animals, especially at moist sites, such as perineum, axillae, and ears.
- Thrives in moist environments of the hospital and in the community, i.e., respiratory equipment, disinfectants, sinks, hot-tubs, contact lens solution.
- Drug resistance is common and multi-drug resistance (MDR) is increasingly common.
- Mechanisms include permeability changes of the outer membrane, efflux pumps, chromosomal and inducible β-lactamases, and acquired genes and plasmid-mediated ESBLs.
- Carbapenem-resistance mechanisms include:
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MICROBIOLOGY
- Aerobic, motile, oxidase-positive, non-fermenting, Gram-negative bacillus.
- Ubiquitous, isolated from soil, water, plants, and animals, especially at moist sites, such as perineum, axillae, and ears.
- Thrives in moist environments of the hospital and in the community, i.e., respiratory equipment, disinfectants, sinks, hot-tubs, contact lens solution.
- Drug resistance is common and multi-drug resistance (MDR) is increasingly common.
- Mechanisms include permeability changes of the outer membrane, efflux pumps, chromosomal and inducible β-lactamases, and acquired genes and plasmid-mediated ESBLs.
- Carbapenem-resistance mechanisms include:
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Last updated: August 29, 2021
Citation
Spacek, Lisa A. "Pseudomonas Aeruginosa." Johns Hopkins HIV Guide, 2021. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545173/all/Pseudomonas_aeruginosa.
Spacek LA. Pseudomonas aeruginosa. Johns Hopkins HIV Guide. 2021. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545173/all/Pseudomonas_aeruginosa. Accessed March 29, 2023.
Spacek, L. A. (2021). Pseudomonas aeruginosa. In Johns Hopkins HIV Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545173/all/Pseudomonas_aeruginosa
Spacek LA. Pseudomonas Aeruginosa [Internet]. In: Johns Hopkins HIV Guide. ; 2021. [cited 2023 March 29]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545173/all/Pseudomonas_aeruginosa.
* Article titles in AMA citation format should be in sentence-case
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