Parvovirus B19
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MICROBIOLOGY
- Viral agent of fifth disease, a childhood exanthem.
- Exposure leads to antibody response with subsequent resistance to further infection.
- 80% of all adults have antibodies to the organism; 65% of HIV-infected adults have antibodies (possibly unable to maintain humoral response).
- Virus has tropism for erythroid precursors in marrow, with pure red blood cell (RBC) aplasia.
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MICROBIOLOGY
- Viral agent of fifth disease, a childhood exanthem.
- Exposure leads to antibody response with subsequent resistance to further infection.
- 80% of all adults have antibodies to the organism; 65% of HIV-infected adults have antibodies (possibly unable to maintain humoral response).
- Virus has tropism for erythroid precursors in marrow, with pure red blood cell (RBC) aplasia.
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