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- Non-motile, non-spore-forming, Gram-negative diplococcus
- Infects cuboidal and columnar epithelium leading to a vigorous inflammatory response
- Selective growth media (Thayer-Martin & New York City) most common; Cx routinely available in Dx of GC infection in settings that can process specimens appropriately. Swabs from urethral, cervical, rectal, pharyngeal, and ocular sites can be Cx’d.
- Non-amplified molecular testing, including EIA and DNA hybridization probes, may be used. Cervical and urethral swabs can be tested.
- Nucleic acid amplification tests (NAATs) are the gold standard and may be performed on urethral swabs, cervical swabs, urine, self-collected vaginal swabs, and rectal and pharyngeal swabs (not FDA approved for rectal and pharyngeal, although excellent test performance).