Johns Hopkins HIV GuideDiagnosisOpportunistic InfectionsParasitic

Microsporidiosis

Khalil Ghanem, M.D., Lisa A. Spacek, M.D., Ph.D.
Microsporidiosis is a topic covered in the Johns Hopkins HIV Guide.

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PATHOGENS

  • Microsporidia is general term for obligate intracellular eukaryotic parasites belonging to phylum Microsporidia.
  • Most commonly identified with human disease:
    • Enterocytozoon bieneusi
    • Encephalitozoon hellem, Encephalitozoon cuniculi & Encephalitozoon intestinalis (syn. Septata intestinalis)
    • Vittaforma corneae
  • Sources of infection & modes of transmission, likely zoonotic and/or waterborne.
  • Spores are quite resistant to environmental conditions and can remain infectious for several years, particularly if protected from desiccation.

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Last updated: January 23, 2014