Johns Hopkins HIV Guide
Herpes zoster
PATHOGENS
- Varicella zoster virus (VZV) is an enveloped, double-stranded DNA, human α-herpesviruses.
- After inhalation, VZV proliferates in the tonsils and and is carried to the epidermis where it causes chicken pox. Then, VZV travels via retrograde transport from sensory nerve terminals to dorsal root and cranial nerve ganglia, and establishes lifelong latent infection.[6]
- VZV reactivates in setting of declining cell-mediated immunity in elderly and immunocompromised individuals, producing herpes zoster (HZ).
- >95% of adult U.S. population infected; in 50% of individuals, VZV reactivation results in HZ by 85 years of age.[5]
There's more to see -- the rest of this topic is available only to subscribers.
Last updated: March 7, 2020
Citation
Spacek, Lisa A. "Herpes Zoster." Johns Hopkins HIV Guide, 2020. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545093/1/Herpes_zoster.
Spacek LA. Herpes zoster. Johns Hopkins HIV Guide. 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545093/1/Herpes_zoster. Accessed December 4, 2023.
Spacek, L. A. (2020). Herpes zoster. In Johns Hopkins HIV Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545093/1/Herpes_zoster
Spacek LA. Herpes Zoster [Internet]. In: Johns Hopkins HIV Guide. ; 2020. [cited 2023 December 04]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545093/1/Herpes_zoster.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Herpes zoster
ID - 545093
A1 - Spacek,Lisa,M.D., Ph.D.
Y1 - 2020/03/07/
BT - Johns Hopkins HIV Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545093/1/Herpes_zoster
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
