Herpes simplex is a topic covered in the Johns Hopkins HIV Guide.

To view the entire topic, please or purchase a subscription.

Johns Hopkins Guides provide diagnosis, management, and treatment guidance for infectious diseases, diabetes, and psychiatric conditions. Explore these free sample topics:

Johns Hopkins Guides

~~ The first section of this topic is shown below ~~


  • HSV-1 and HSV-2 are double-stranded, enveloped DNA viruses of the α-herpesviruses. Distributed worldwide, HSV-1 and HSV-2 are antigenically distinct. Herpes from Greek "to creep".
  • High rates of seroprevalence to HSV-1 by adulthood, seroprevalence of HSV-2 related to sexual activity. HSV-2 increases risk of HIV acquisition and transmission.
  • A chronic, life-long infection with acute episodes; establishes latency in sensory ganglia at site of initial mucocutaneous infection.

~~ To view the remaining sections of this topic, please
or purchase a subscription ~~

Last updated: February 1, 2015