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    Herpes simplex

    Lisa A. Spacek, M.D., Ph.D.
    Herpes simplex is a topic covered in the Johns Hopkins HIV Guide.

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    PATHOGENS

    • HSV-1 and HSV-2 are double-stranded, enveloped DNA viruses of the α-herpesviruses. Distributed worldwide, HSV-1 and HSV-2 are antigenically distinct. Herpes from Greek "to creep".
    • High rates of seroprevalence to HSV-1 by adulthood, seroprevalence of HSV-2 related to sexual activity. HSV-2 increases risk of HIV acquisition and transmission.
    • A chronic, life-long infection with acute episodes; establishes latency in sensory ganglia at site of initial mucocutaneous infection.

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    Last updated: February 1, 2015

    Citation

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    TY - ELEC T1 - Herpes simplex ID - 545092 A1 - Spacek,Lisa,M.D., Ph.D. Y1 - 2015/02/01/ BT - Johns Hopkins HIV Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545092/all/Herpes_simplex DB - Johns Hopkins Guide DP - Unbound Medicine ER -