Cyclospora cayetanensis

Cyclospora cayetanensis is a topic covered in the Johns Hopkins HIV Guide.

To view the entire topic, please or purchase a subscription.

Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Explore these free sample topics:

Johns Hopkins Guides

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Obligate intracellular coccidian parasite; infects epithelial cells of small intestine. Destroys brush border and alters mucosal architecture.[4]
  • Excreted in stool as oocysts (spherical, 8-10 μm in diameter), which may be shed intermittantly and at low levels. Sporulation (maturation of oocysts) occurs outside host and takes 7-12d.
  • Transmitted by fecal-contaminated soil, food and water. Humans only known host and reservoir. Human-to-human transmission unlikely as excreted oocysts must sporulate before becoming infectious.
  • Both sporadic infections and outbreaks occur. Frequency peaks during spring & summer in the U.S., associated with fruits and vegetables, i.e., raspberries, mixed salad greens, cilantro, and basil.[5]
    • 2018 outbreak season comprised 2 multistate outbreaks and 761 laboratory-confirmed cases.[6]
  • Lack of validated molecular typing tool limits outbreak investigations.[6]
  • Endemic areas, i.e., Peru, Nepal, Haiti, Guatemala, Indonesia. Low-level endemicity in US cannot be excluded.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: July 1, 2019