Johns Hopkins HIV Guide
CMV, gastrointestinal
PATHOGENS
- Member of Betaherpesviridae, double-stranded DNA virus; 60-100% seroprevalence.
- Most infections asymptomatic, viral replication and shedding without symptoms. Severe disease seen in HIV CD4 < 50.
- Transmitted vertically, sexually or by close contact (family members, daycare) via blood, tears, saliva, breast milk, urine, cervical secretions and semen.
- Establishes permanent latent infection in host.
- Most cases in immunosuppressed adults due to reactivation.
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Last updated: April 2, 2019
Citation
Spacek, Lisa A. "CMV, Gastrointestinal." Johns Hopkins HIV Guide, 2019. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545042/all/CMV__gastrointestinal.
Spacek LA. CMV, gastrointestinal. Johns Hopkins HIV Guide. 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545042/all/CMV__gastrointestinal. Accessed September 21, 2023.
Spacek, L. A. (2019). CMV, gastrointestinal. In Johns Hopkins HIV Guide https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545042/all/CMV__gastrointestinal
Spacek LA. CMV, Gastrointestinal [Internet]. In: Johns Hopkins HIV Guide. ; 2019. [cited 2023 September 21]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545042/all/CMV__gastrointestinal.
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