Chlamydia trachomatis

Chlamydia trachomatis is a topic covered in the Johns Hopkins HIV Guide.

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  • The many serovars of C. trachomatis can generally be divided into the trachoma biovar (serovars A - K) causing genital tract disease, conjunctivitis, and trachoma (inflammation of inner eyelids) and the LGV biovar (serovars L1 - L3) causing lymphogranuloma venereum and proctocolitis.
  • Obligate intracellular bacteria, infecting primarily ocular and genitourinary epithelium; one of the smallest known bacterial genomes.
  • All Chlamydia species have 2 distinct forms in their infectious cycle: elementary body (EB - infectious, extracellular sporelike form) and reticulate body (RB - intracellular, replicating form).
  • Requires cell culture for propagation.
  • Immunity is not long-lived.

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Last updated: August 2, 2017