Johns Hopkins HIV Guide
Chlamydia trachomatis
Chlamydia trachomatis is a topic covered in the Johns Hopkins HIV Guide.
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MICROBIOLOGY
- The many serovars of C. trachomatis can generally be divided into the trachoma biovar (serovars A - K) causing genital tract disease, conjunctivitis, and trachoma (inflammation of inner eyelids) and the LGV biovar (serovars L1 - L3) causing lymphogranuloma venereum and proctocolitis.
- Obligate intracellular bacteria, infecting primarily ocular and genitourinary epithelium; one of the smallest known bacterial genomes.
- All Chlamydia species have 2 distinct forms in their infectious cycle: elementary body (EB - infectious, extracellular sporelike form) and reticulate body (RB - intracellular, replicating form).
- Requires cell culture for propagation.
- Immunity is not long-lived.
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MICROBIOLOGY
- The many serovars of C. trachomatis can generally be divided into the trachoma biovar (serovars A - K) causing genital tract disease, conjunctivitis, and trachoma (inflammation of inner eyelids) and the LGV biovar (serovars L1 - L3) causing lymphogranuloma venereum and proctocolitis.
- Obligate intracellular bacteria, infecting primarily ocular and genitourinary epithelium; one of the smallest known bacterial genomes.
- All Chlamydia species have 2 distinct forms in their infectious cycle: elementary body (EB - infectious, extracellular sporelike form) and reticulate body (RB - intracellular, replicating form).
- Requires cell culture for propagation.
- Immunity is not long-lived.
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Last updated: August 2, 2017
Citation
Antar, Annie, and Emily J Erbelding. "Chlamydia Trachomatis." Johns Hopkins HIV Guide, 2017. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545032/all/Chlamydia_trachomatis.
Antar A, Erbelding EJ. Chlamydia trachomatis. Johns Hopkins HIV Guide. 2017. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545032/all/Chlamydia_trachomatis. Accessed January 26, 2020.
Antar, A., & Erbelding, E. J. (2017). Chlamydia trachomatis. In Johns Hopkins HIV Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545032/all/Chlamydia_trachomatis
Antar A, Erbelding EJ. Chlamydia Trachomatis [Internet]. In: Johns Hopkins HIV Guide. ; 2017. [cited 2020 January 26]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545032/all/Chlamydia_trachomatis.
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