Chlamydia trachomatis is a topic covered in the Johns Hopkins HIV Guide.

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MICROBIOLOGY

  • Four biovars of C. trachomatis cause human infection and clinical disease (trachoma, lymphogranuloma venereum, urogenital infections, etc.).
  • Obligate intracellular parasite, requires eukaryotic host cell for ATP; cultivated only within cell cultured system.
  • 2 distinct mophologic cycles: elementary body (metabolically inert extracellular infectious particle) and reticulate body (intracellular, replicating form).
  • Commonest syndromes in HIV practice involve C. trachomatis serovars infecting columnar or cuboidal epithelial surfaces.

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Last updated: April 25, 2011