Antiretroviral Therapy: Treatment-Experienced Patients

Antiretroviral Therapy: Treatment-Experienced Patients is a topic covered in the Johns Hopkins HIV Guide.

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DEFINITION

  • Use of ART in pts with hx of virologic failure on previous regimen(s).[4]
    • Virologic suppression: confirmed viral load (VL) below limit of assay detection.
    • Virologic failure (VF): two consecutive VL > 200 c/ml after 24 wks on ART.
    • Immunologic failure: failure to achieve and maintain adequate CD4 increase despite viral suppression.

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DEFINITION

  • Use of ART in pts with hx of virologic failure on previous regimen(s).[4]
    • Virologic suppression: confirmed viral load (VL) below limit of assay detection.
    • Virologic failure (VF): two consecutive VL > 200 c/ml after 24 wks on ART.
    • Immunologic failure: failure to achieve and maintain adequate CD4 increase despite viral suppression.

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Last updated: October 3, 2015