Algorithm for Sequencing Glucose-Lowering Therapies in Type 2 Diabetes
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- Glycemic management in type 2 diabetes is complex and evolving, with many new therapies for type 2 diabetes having been introduced over the past few years.
- More recent guidelines emphasize a patient-centered approach and also take into consideration patient factors when choosing therapies and appropriate glycemic goals (i.e. patient involvement and expected efforts; comorbidities, especially established vascular complications; disease duration; life expectancy).
- Other factors to consider when choosing therapies for type 2 diabetes might include: efficacy, cost, available resources and support system, fasting versus postprandial hyperglycemia, risk of hypoglycemia, weight changes, drug side effects, route of administration, and drug’s mechanism of action.