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- Pheochromocytoma is a rare but potentially life-threatening cause of secondary diabetes mellitus
- Pheochromoctyomas are catecholamine-producing neuroendocrine tumors which arise from chromaffin cells of the adrenal medulla or extra-adrenal paraganglia.
- Extra-adrenal chromaffin tissue tumors are referred to as paragangliomas or extra-adrenal pheochromocytomas.
- 80-85% pheochromocytomas originate from the adrenal medulla, and 15-20% arises from paragangliomas.