Immunomodulating Therapies in Type 1 Diabetes
Immunomodulating Therapies in Type 1 Diabetes is a topic covered in the Johns Hopkins Diabetes Guide.
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DEFINITION
- Type 1 diabetes mellitus (T1DM) is an autoimmune disease.
- Destruction of insulin producing beta-cells by T cells renders patients insulin-deficient.
- Exogenous insulin is therefore required for T1DM management of hyperglycemia and to prevent ketoacidosis[19].
- Several immunomodulating therapies have been investigated in research studies over the last decades with the goal of preventing, postponing or reversing the onset of T1DM by slowing or stopping the immune-mediated destruction of beta-cells.
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Last updated: September 4, 2017
Citation
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TY - ELEC
T1 - Immunomodulating Therapies in Type 1 Diabetes
ID - 547160
A1 - Donner,Thomas,M.D.
AU - Lee,Clare,M.D., MHS
AU - Quartuccio,Michael,M.D.
Y1 - 2017/09/04/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547160/all/Immunomodulating_Therapies_in_Type_1_Diabetes
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -