Post-Pancreatectomy Diabetes

Erica Hall, MSN, ANP-BC, CDE, Joanne Dintzis, C.R.N.P., C.D.E., Rita Rastogi Kalyani, M.D., M.H.S.


  • Endocrine pancreatic insufficiency occurring after surgical resection of the pancreas
  • Includes the development of new-onset diabetes, exacerbation of pre-existing diabetes, or progression of pre-existing glucose intolerance to overt diabetes
  • Important factors include: amount of pancreatic parenchymal tissue removed, resection vs "sparing" of adjacent organs, preoperative pancreatic function, peripheral insulin resistance, preoperative diabetes, and postoperative changes in nutrition.

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Last updated: November 2, 2015