Johns Hopkins Diabetes Guide
Mitochondrial diabetes
DEFINITION
- Mutations in the mitochondrial genome (mtDNA) can cause diabetes mellitus (DM).
- The distinguishing clinical feature of mitochondrial diabetes is in association with other symptoms, including hearing impairment, neurological disorders, cardiac failure, and renal failure.
- These mutations can be large deletions, duplications, rearrangements, or point mutations.
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Last updated: April 2, 2019
Citation
Cooke, David, et al. "Mitochondrial Diabetes." Johns Hopkins Diabetes Guide, The Johns Hopkins University, 2019. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547094/0/Mitochondrial_diabetes.
Cooke D, Akhtar Y, Mohamadi A. Mitochondrial diabetes. Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2019. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547094/0/Mitochondrial_diabetes. Accessed November 4, 2025.
Cooke, D., Akhtar, Y., & Mohamadi, A. (2019). Mitochondrial diabetes. In Johns Hopkins Diabetes Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547094/0/Mitochondrial_diabetes
Cooke D, Akhtar Y, Mohamadi A. Mitochondrial Diabetes [Internet]. In: Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2019. [cited 2025 November 04]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547094/0/Mitochondrial_diabetes.
* Article titles in AMA citation format should be in sentence-case
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T1 - Mitochondrial diabetes
ID - 547094
A1 - Cooke,David,M.D.
AU - Akhtar,Yasmin,DO, MPH
AU - Mohamadi,Ali,M.D.
Y1 - 2019/04/02/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547094/0/Mitochondrial_diabetes
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -
