Dermatologic Manifestations of Diabetes

Shivani Patel, M.D., Meg Gerstenblith, M.D., Mimi Huizinga, M.D.


  • Dermatologic manifestations of diabetes are common and vary in clinical presentation[12].
  • Skin findings may help diagnose diabetes (e.g. acanthosis nigricans) or reflect long-term complications of diabetes (e.g. necrobiosis lipoidica diabeticorum [NLD]).
  • The dermatologic manifestations may be due to deposition of advanced glycosylation end-products (AGEs), infection, autoimmune conditions, or related to pharmacological therapy for diabetes (i.e. insulin).
  • Often, skin manifestations reflect other coexisting conditions such as dyslipidemia.

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Last updated: April 28, 2018