Charcot Joint Disease (diabetic neuropathic osteoarthropathy)
DEFINITION
- Diabetic neuropathic osteoarthropathy is commonly known as Charcot neuropathic osteoarthropathy (CN), Charcot joint disease (CJD) or the Charcot foot.[14][4]
- A potentially disabling complication of diabetes, it creates a local osteopenic reaction. The weakened bone continues to bear weight and this results in deformity and instability of the foot and/or ankle.
- As the bones collapse, the deformity can subsequently create a "rocker bottom" deformity, ulceration, or infection, and can ultimately lead to amputation.
- Active (acute) condition: a sudden, unexpected and often misdiagnosed neuropathic arthropathy, often preceded by unrecognized minor trauma; characterized by rapidly progressive localized inflammation with erythema, swelling, elevated skin temperature and associated with sterile destruction of joints including subluxation, dislocation, fractures, osteolysis and foot deformity.
- Inactive (chronic) condition: Characterized by resolution of inflammation, exuberant ossification, increased bone density, restoration of stability and foot deformity.
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Last updated: July 4, 2020
Citation
Shin, Laura, et al. "Charcot Joint Disease (diabetic Neuropathic Osteoarthropathy)." Johns Hopkins Diabetes Guide Johns Hopkins Diabetes Guide, The Johns Hopkins University, 2020. Johns Hopkins Guides, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Diseasediabetic_neuropathic_osteoarthropathy_.
Shin L, Armstrong D, Sanders LJ. Charcot Joint Disease (diabetic neuropathic osteoarthropathy). Johns Hopkins Diabetes Guide Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Diseasediabetic_neuropathic_osteoarthropathy_. Accessed October 2, 2026.
Shin, L., Armstrong, D., & Sanders, L. J. (2020). Charcot Joint Disease (diabetic neuropathic osteoarthropathy). In Johns Hopkins Diabetes Guide Johns Hopkins Diabetes Guide. The Johns Hopkins University. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Diseasediabetic_neuropathic_osteoarthropathy_
Shin L, Armstrong D, Sanders LJ. Charcot Joint Disease (diabetic Neuropathic Osteoarthropathy) [Internet]. In: Johns Hopkins Diabetes Guide Johns Hopkins Diabetes Guide. The Johns Hopkins University; 2020. [cited 2026 October 02]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Diseasediabetic_neuropathic_osteoarthropathy_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Charcot Joint Disease (diabetic neuropathic osteoarthropathy)
ID - 547027
A1 - Shin,Laura,D.P.M., Ph.D.
AU - Armstrong,David,D.P.M., M.D., Ph.D.
AU - Sanders,Lee,D.P.M.
Y1 - 2020/07/04/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Diseasediabetic_neuropathic_osteoarthropathy_
PB - The Johns Hopkins University
DB - Johns Hopkins Guides
DP - Unbound Medicine
ER -

Johns Hopkins Diabetes Guide

