Johns Hopkins Diabetes GuideComplications and ComorbiditiesMuscle Skin and Bone

Charcot Joint Disease (diabetic neuropathic osteoarthropathy)

Lee J. Sanders, D.P.M.
Charcot Joint Disease (diabetic neuropathic osteoarthropathy) is a topic covered in the Johns Hopkins Diabetes Guide.

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  • Diabetic neuropathic osteoarthropathy is commonly known as Charcot neuropathic osteoarthropathy (CN), Charcot joint disease (CJD) or the Charcot foot. [11] [2]
  • A potentially disabling complication of diabetes, it results in deformity and instability of the foot and/or ankle, can subsequently develop ulceration and infection, and can ultimately lead to amputation.
  • Active (acute) condition: a sudden, unexpected and often misdiagnosed neuropathic arthropathy, often preceded by unrecognized minor trauma; characterized by rapidly progressive localized inflammation with erythema, swelling, elevated skin temperature and associated with joint subluxation, dislocation, fractures, osteolysis and foot deformity.
  • Inactive (chronic) condition: Characterized by resolution of inflammation, exuberant ossification, increased bone density, restoration of stability and foot deformity.

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Last updated: February 2, 2015