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Charcot Joint Disease (diabetic neuropathic osteoarthropathy)

Lee J. Sanders, D.P.M.
Charcot Joint Disease (diabetic neuropathic osteoarthropathy) is a topic covered in the Johns Hopkins Diabetes Guide.

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  • Diabetic neuropathic osteoarthropathy is commonly known as Charcot neuropathic osteoarthropathy (CN), Charcot joint disease (CJD) or the Charcot foot.[11][2]
  • A potentially disabling complication of diabetes, it results in deformity and instability of the foot and/or ankle, can subsequently develop ulceration and infection, and can ultimately lead to amputation.
  • Active (acute) condition: a sudden, unexpected and often misdiagnosed neuropathic arthropathy, often preceded by unrecognized minor trauma; characterized by rapidly progressive localized inflammation with erythema, swelling, elevated skin temperature and associated with joint subluxation, dislocation, fractures, osteolysis and foot deformity.
  • Inactive (chronic) condition: Characterized by resolution of inflammation, exuberant ossification, increased bone density, restoration of stability and foot deformity.

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Last updated: February 2, 2015


Sanders, Lee J. "Charcot Joint Disease (diabetic Neuropathic Osteoarthropathy)." Johns Hopkins Diabetes Guide, 2015. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Disease__diabetic_neuropathic_osteoarthropathy_.
Sanders LJ. Charcot Joint Disease (diabetic neuropathic osteoarthropathy). Johns Hopkins Diabetes Guide. 2015. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Disease__diabetic_neuropathic_osteoarthropathy_. Accessed July 18, 2019.
Sanders, L. J. (2015). Charcot Joint Disease (diabetic neuropathic osteoarthropathy). In Johns Hopkins Diabetes Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Disease__diabetic_neuropathic_osteoarthropathy_
Sanders LJ. Charcot Joint Disease (diabetic Neuropathic Osteoarthropathy) [Internet]. In: Johns Hopkins Diabetes Guide. ; 2015. [cited 2019 July 18]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Disease__diabetic_neuropathic_osteoarthropathy_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Charcot Joint Disease (diabetic neuropathic osteoarthropathy) ID - 547027 A1 - Sanders,Lee,D.P.M. Y1 - 2015/02/02/ BT - Johns Hopkins Diabetes Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547027/all/Charcot_Joint_Disease__diabetic_neuropathic_osteoarthropathy_ DB - Johns Hopkins Guide DP - Unbound Medicine ER -