Cancer and Diabetes
Cancer and Diabetes is a topic covered in the Johns Hopkins Diabetes Guide.
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EPIDEMIOLOGY
Incident Cancer:
Incident Cancer:
Diabetes and cancer death
Diabetes and cancer death
- Diabetes associated with:
- increased risk of death from colon and pancreatic cancer in both men and women;
- increased risk of death from liver and bladder cancers in men,
- increased risk of death from breast cancer in women[38]
- Also reported positive associations with death from:
- esophagus, liver, and colon/rectum cancers in men, and
- liver and cervix cancers in women[36]
Diabetes in Cancer Patients
Diabetes in Cancer Patients
- Meta-analyses showed diabetes associated with an increased mortality in patients with any cancer [HR of 1.44], cancers of the endometrium (HR, 1.76), breast (HR, 1.61), colorectum (HR, 1.32), and prostate[13][10].
- Meta-analysis showed diabetes associated with increased odds of postoperative mortality across all cancer types [HR=1.5][13].
- Hyperglycemia associated with shorter duration of complete remission in patients with acute lymphocytic leukemia[37].
- Hyperglycemia associated with shorter survival in patients with newly diagnosed glioblastoma[17].
Diabetes and Prostate Cancer
Diabetes and Prostate Cancer
Obesity and Cancer
Obesity and Cancer
- A meta-analysis[23] showed BMI strongly associated with:
- oesophageal adenocarcinoma (RR 1.52), thyroid (RR 1.33), colon (RR 1.24), and renal (RR 1.24) cancers. (all p< 0.001 )
- endometrial (RR 1.59), gallbladder (RR 1.59), esophageal (RR 1.51), and renal (RR 1.34) cancers in women. (all p< 0.05)
- weaker positive associations with cancer and malignant melanoma in men
- Patients with gastric bypass surgery had a lower risk of cancer incidence and mortality compared to severely obese patients[27][19]
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Last updated: June 24, 2013
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TY - ELEC
T1 - Cancer and Diabetes
ID - 547023
A1 - Brancati,Frederick,M.D., M.H.S.
AU - Yeh,Hsin-Chieh,Ph.D.
Y1 - 2013/06/24/
BT - Johns Hopkins Diabetes Guide
UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547023/all/Cancer_and_Diabetes
DB - Johns Hopkins Guide
DP - Unbound Medicine
ER -