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Autonomic Neuropathy

Nima Khoshnoodi, M.D., Michael Polydefkis, M.D., M.H.S., Kathy Burks, C.R.N.P.
Autonomic Neuropathy is a topic covered in the Johns Hopkins Diabetes Guide.

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  • Diabetic autonomic neuropathy (DAN) is a common, under appreciated complication of diabetes with significant negative impact on survival and quality of life.
  • Involvement of autonomic nerves in diabetes follows a length-dependent pattern. The longest autonomic nerve - the vegus nerve - is the first affected, and provides 75% of parasympathetic tone, with a broad range of effects.
  • Later, loss of sympathetic nerve function can also occur.

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Last updated: September 25, 2016


Khoshnoodi, Nima, et al. "Autonomic Neuropathy." Johns Hopkins Diabetes Guide, 2016. Johns Hopkins Guide, www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547014/all/Autonomic_Neuropathy.
Khoshnoodi , Polydefkis M, Burks K. Autonomic Neuropathy. Johns Hopkins Diabetes Guide. 2016. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547014/all/Autonomic_Neuropathy. Accessed July 22, 2019.
Khoshnoodi, ., Polydefkis, M., & Burks, K. (2016). Autonomic Neuropathy. In Johns Hopkins Diabetes Guide. Available from https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547014/all/Autonomic_Neuropathy
Khoshnoodi , Polydefkis M, Burks K. Autonomic Neuropathy [Internet]. In: Johns Hopkins Diabetes Guide. ; 2016. [cited 2019 July 22]. Available from: https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547014/all/Autonomic_Neuropathy.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Autonomic Neuropathy ID - 547014 A1 - Khoshnoodi, Nima,M.D. AU - Polydefkis,Michael,M.D., M.H.S. AU - Burks,Kathy,C.R.N.P. Y1 - 2016/09/25/ BT - Johns Hopkins Diabetes Guide UR - https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547014/all/Autonomic_Neuropathy DB - Johns Hopkins Guide DP - Unbound Medicine ER -