Autonomic Neuropathy

Gerard Limerick, M.D., PhD, Nima Khoshnoodi, M.D.


  • Diabetic autonomic neuropathy (DAN) is a common, under-appreciated complication of diabetes with significant negative impact on survival and quality of life.
  • Involvement of autonomic nerves in diabetes follows a length-dependent pattern. The longest autonomic nerve - the vegus nerve - is the first affected, and provides 75% of parasympathetic tone, with a broad range of effects.
  • Later, loss of sympathetic nerve function can also occur.

There's more to see -- the rest of this topic is available only to subscribers.

Last updated: September 3, 2023