Dalbavancin

Kathryn Dzintars, Pharm.D., BCPS

INDICATIONS

FDA

  • Treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible Gram-positive organisms.
    • S. aureus(including MRSA), S. pyogenes, S. agalactiae, S. dysgalactiae, S. anginosus group, E. faecalis (vancomycin-susceptible)

NON-FDA APPROVED USES

  • Not FDA-approved for bacteremia[2], endocarditis (right-sided), osteomyelitis[5], prosthetic joint infection, and/or other invasive gram-positive infections
    • Off-label use is supported by growing observational data and limited randomized evidence, but optimal patient selection and dosing remain unsettled

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Last updated: October 18, 2026